Nika Adham Selected Research

cariprazine

9/2021	Cariprazine alleviates core behavioral deficits in the prenatal valproic acid exposure model of autism spectrum disorder.
1/2021	Preferential Effects of Cariprazine on Counteracting the Disruption of Social Interaction and Decrease in Extracellular Dopamine Levels Induced by the Dopamine D3 Receptor Agonist, PD-128907 in Rats: Implications for the Treatment of Negative and Depressive Symptoms of Psychiatric Disorders.
10/2020	Long-term administration of cariprazine increases locus coeruleus noradrenergic neurons activity and serotonin1A receptor neurotransmission in the hippocampus.
1/2020	The novel antipsychotic cariprazine stabilizes gamma oscillations in rat hippocampal slices.
11/2019	The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens.
12/2018	The novel atypical antipsychotic cariprazine demonstrates dopamine D2 receptor-dependent partial agonist actions on rat mesencephalic dopamine neuronal activity.
12/2018	Involvement of 5-HT1A and 5-HT2A Receptors but Not α 2-Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo.
1/2018	Effects of cariprazine on extracellular levels of glutamate, GABA, dopamine, noradrenaline and serotonin in the medial prefrontal cortex in the rat phencyclidine model of schizophrenia studied by microdialysis and simultaneous recordings of locomotor activity.
12/2017	Long-term effects of aripiprazole exposure on monoaminergic and glutamatergic receptor subtypes: comparison with cariprazine.
10/2017	Cariprazine Exhibits Anxiolytic and Dopamine D3 Receptor-Dependent Antidepressant Effects in the Chronic Stress Model.

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Nika Adham Research Topics

Disease

15	Schizophrenia (Dementia Praecox) 09/2021 - 03/2013
5	Bipolar Disorder (Manic Depressive Psychosis) 01/2021 - 09/2015
3	Mania (Manias) 12/2017 - 02/2015
2	Major Depressive Disorder (Major Depressive Disorders) 10/2020 - 10/2017
2	Anhedonia 10/2017 - 09/2014
1	Autism Spectrum Disorder 09/2021
1	Mental Disorders (Mental Disorder) 01/2021
1	Neurobehavioral Manifestations 02/2016
1	Cognitive Dysfunction 03/2013

Drug/Important Bio-Agent (IBA)

17	cariprazineIBA 09/2021 - 03/2013
14	Dopamine (Intropin)FDA LinkGeneric 09/2021 - 03/2013
5	Antipsychotic Agents (Antipsychotics)IBA 01/2020 - 02/2015
4	Dopamine D3 ReceptorsIBA 01/2021 - 10/2016
3	Serotonin (5 Hydroxytryptamine)IBA 10/2020 - 12/2017
3	Phencyclidine (Angel Dust)IBA 01/2018 - 03/2013
2	3,4,4a,10b- tetrahydro- 4- propyl- 2H,5H- (1)benzopyrano(4,3- b)- 1,4- oxazin- 9- olIBA 01/2021 - 11/2019
2	Glutamic Acid (Glutamate)FDA Link 01/2018 - 01/2018
1	Valproic Acid (Depakote)FDA LinkGeneric 09/2021
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2018
1	gamma-Aminobutyric Acid (GABA)IBA 01/2018
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2018
1	Glutamate Receptors (Glutamate Receptor)IBA 12/2017
1	Aripiprazole (Abilify)FDA Link 10/2017
1	Imipramine (Janimine)FDA LinkGeneric 10/2017
1	LigandsIBA 10/2016
1	Dopamine Receptors (Dopamine Receptor)IBA 02/2016
1	Ouabain (G Strophanthin)IBA 02/2015
1	LithiumIBA 02/2015
1	Antidepressive Agents (Antidepressants)IBA 09/2014
1	Pharmaceutical PreparationsIBA 03/2013

Therapy/Procedure

1	Therapeutics 10/2020